Dermal Sign E+

In Malaysia, Dermal Sign E+ is a high-end skin booster. K-pop stars and other celebrities in Korea use these products, which are developed in Korea. It is listed in over 20 countries across the globe. It is the most effective melasma treatment.

For those seeking a clearer complexion and pigmentation-free skin, Dermal Sign E+ is a semi-cross-linked hyaluronic acid-based intensive solution skin booster that helps develop exceptional and long-lasting brightening effects. This high-quality skin booster contains three brightening ingredients: AA2G (antioxidant effect of stabilised Vitamin C), tranexamic acid (a brightening ingredient primarily used in medicine for the therapy of pigmentation), and glutathione (a water-soluble ingredient).

In a brightening effect test, clinical data indicates that Dermal Sign E+ is superior to Arbutin (a cosmeceutical that fades hyperpigmentation) in helping to reduce the production of melanin (pigmentation). Tyrosinase is reduced by 59.5% following the initial treatment for Dermal Sign E+. Tyrosinase is the enzyme that initiates the synthesis of melanin, so inhibiting it can greatly improve the appearance of dark spots (pigmentation, melasma, chloasma).

Furthermore, in conjunction with Diamond Feel Forte, the skin’s ability to repair itself more quickly and maintain its firmness, hydration, and anti-inflammatory properties will all be enhanced.

Table of Contents

Play Video

Benefits of Dermal Sign E+

Therapy for pigmentation conditions like age spots, melasma, freckles, and post-inflammatory pigmentation from acne

Triple Illumination Ingredients with exceptional brightening power and long-lasting results

Elasticity of Skin and Collagen Booster

Brighter, more radiant skin

Ideal for people with skin conditions like pigmentation

  • Acne Scars & open pores 
  • Dry and dehydrated skin 
  • Fine wrinkles and lines 
  • Aging problems 
  • texture problems 
  • Pigmentation 
  • Freckles, melasma 
  • Dark eye circles 
  • Redness 
  • Overall face for facial complexion 
  • Dark spots

Why does the Dermal Sign E+ treatment work so well?

The ingredients are safe and suitable for Muslims. It contains tranexamic acid, which is mostly used for pigmentation, AA2G, which has antioxidant qualities, and glutathione, a water-soluble brightening ingredient. Moreover, it has semi-cross-linked hyaluronic acid, which fortifies the skin barrier, retains moisture, and supplies moisture.


How many treatments do I need?

4 sessions at 2-3 weeks interval in initial stage. Every 6 months to 12 months for maintenance.

Before & After Patient Testimonial

Watch How The Procedure Done

Why Choose Us ?

As one of the Leading Aesthetic Clinic in Malaysia, NextMed Clinic provides top-notch procedures by Certified Medical Practitioners. Whatever your concerns, be it enhancing your natural features or reversing the signs of aging, NextMed Clinic is able to deliver a wide range of quality, state of art & personalized aesthetic, general health services & wellness solution, merged with exemplary service, in a warm and pleasent enviroment designed to make you feel completely at ease.

At NextMed Clinic, we strongly believe that each patient is unique. Therefore treatments are customized to each patient’s specific needs.

Certified Doctor


Safe and Effective Methods
Minimal downtime
5-star rating